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Bullous Pemphigoid

A rare, chronic autoimmune disease with telltale large, fluid-filled blisters on the skin, commonly appearing on the lower abdomen, upper thighs or armpits.

What is it?

This uncommon condition sometimes begins with sore, red and itchy patches prior to the emergence of blisters. These patches may appear as either red or pink, or a dark reddish brown. Bullous pemphigoid causes your immune system to mistakenly attack the fibrous cells that connect your epidermis (the skin's outermost layer) to deeper skin tissue, called the dermis. This attack results in inflamation of the connective fibers, resulting in rashes and blistering.


The disease typically emerges in adults over the age of 60 and may be triggered by certain medications, allergies, diet or lifestyle, medical treatments – like radiation or chemotherapy or surgeries – or certain medical conditions that may trigger bullous pemphigoid, including psoriasis, lichen planus, diabetes, rheumatoid arthritis, ulcerative colitis and multiple sclerosis.


How is it treated?

Bullous pemphigoid typically resolves on its own, though it may take several years to completey resolve. Various therapies are available to promote skin healing, alleviate itching, prevent new patches or blisters and lower the risk of skin infections. Initial treatment options may involve topical steroids, systemic steroids, antibiotics and pain relief medications.


If left unaddressed, bullous pemphigoid can lead to severe health complications, particularly in individuals with compromised immune systems or underlying medical conditions. These complications may include skin infections and adverse effects from steroid treatments.


Despite initial treatment attempts, many patients continue to experience persistent symptoms, necessitating more advanced medical interventions. Our specialized team employs a unique blend of research-driven approaches and innovative treatments to provide relief, even for those who have not responded to previous therapies. If you seek lasting relief from conditions like bullous pemphigoid, schedule a consultation at our conveniently located practice in Chicago, Illinois.


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